Chief Medical Officer (CMO)
Ottignies-Louvain-La-Neuve,
Belgium
Why this role matters
As a Chief Medical Officer, you will be accountable for Inteliphage’s medical strategy and for the clinical development of its Phage Therapy Medicinal Product (PTMP) portfolio. You will convert an advanced clinical concept into executable protocols, high-quality trials, interpretable evidence and registration-ready clinical dossiers.
Working closely with the CEO, CBO and CSO, you integrate clinical medicine, clinical operations, regulatory medicine, pharmacovigilance, medical affairs, publications and commercial medical education. You will also be a visible external representative of Inteliphage in hospitals, clinical societies and the international infectious-disease community.
What your days could look like
Clinical strategy completion and execution
- Lead and work closely with our Clinical Advisory Board to define and finalise key clinical questions, including patient populations, sub-indication grouping, endpoints, biomarkers, timing and practical implementation.
- Translate the clinical strategy into regulator-ready and site-executable studies.
- Maintain a coherent route from First-in-Human studies to pivotal development and registration.
Medical affairs and external clinical leadership
- Build Inteliphage’s medical affairs capability.
- Develop relationships with KOLs, regulators, investigators, societies, hospitals and clinical microbiology networks.
- Represent Inteliphage at scientific congresses, advisory boards and expert meetings.
- Lead publication planning and timely dissemination of clinical results in peer-reviewed literature.
Clinical development leadership
- Finalize the Clinical Development Plan, Target Product Profiles and indication-specific evidence plans.
- Lead protocol development, investigator brochures, clinical sections of regulatory dossiers and clinical study reports.
- Oversee Phase I–III execution, including medical monitoring, eligibility decisions, endpoint interpretation and benefit-risk assessment.
- Ensure strong interfaces with clinical operations, statistics, data management, pharmacology, CMC and regulatory affairs.
Medical education for Business Development teams
- Design and deliver structured medical training for Business Development teams.
- Ensure teams understand disease pathways, unmet need, PTMP mechanism and use, clinical evidence, appropriate scientific claims and escalation of medical questions.
- Develop field medical materials and maintain scientific consistency in hospital-facing interactions.
Patient safety and regulatory medicine
- Provide medical oversight of pharmacovigilance and safety management.
- Lead medical contributions to EMA and other authority interactions, ethics committees and clinical trial applications.
- Maintain an evidence-based benefit-risk framework across the product lifecycle.
Medical strategy and governance
- Own and execute the company-wide medical strategy.
- Establish medical governance, safety escalation, evidence review and protocol decision processes.
- Advise the Executive Leadership Team and Board on medical risk, opportunity and development choices.
European clinical partnerships and programme financing
- • Convert the existing Clinical Advisory Board and hospital network into trial-specific European consortia for BJI, acute and chronic LRTI.
- • Own the clinical rationale, protocol architecture, site model, recruitment assumptions and clinical budgets used in Horizon Europe, IHI and complementary funding applications.
- • Identify and medically qualify national, disease-specific and investigator-led funding opportunities that can finance defined components of the five-trial program.
- • Ensure that consortium agreements, clinical trial agreements and data-access arrangements provide Inteliphage with the rights required to use the complete clinical evidence package in regulatory submissions.
- • Work with the CEO, CBO, CSO, Finance, Regulatory and program-management functions to elaborate and monitor funding plans
What you bring to the table
- Education and clinical credentials
- • Medical degree with specialist training in infectious diseases strongly preferred.
- • Internal medicine, clinical microbiology, pulmonology, intensive care or another relevant specialty may be considered if combined with deep anti-infective expertise.
- • PhD, clinical research doctorate or equivalent academic track record is highly desirable.
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- Professional experience
- • Typically 10+ years of combined clinical, academic and/or pharmaceutical development experience.
- • Experience designing and leading multicenter interventional studies, preferably in infectious diseases or anti-infectives.
- • Experience building multinational investigator networks and contributing to public, charitable or collaborative clinical-research funding applications is strongly preferred.
- • Demonstrated clinical development experience from early phase through pivotal studies and registration.
- • Experience with EMA and/or other health-authority interactions, GCP, medical monitoring and benefit-risk assessment.
- • Publication record and recognized network among clinicians and KOLs.
- • Experience with biologics, precision medicine, companion diagnostics or personalized therapies is advantageous.
- • Bacteriophage experience is beneficial but not required.
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- Leadership profile
- • Clinically credible, patient-centered and scientifically rigorous.
- • Able to convert complex concepts into executable clinical programs.
- • Strong communicator with investigators, regulators, employees, commercial colleagues and external stakeholders.
- • Visible and persuasive medical ambassador, without compromising scientific accuracy or compliance.
- • Comfortable in an entrepreneurial scale-up environment.
- • Fluent professional English; French and/or Dutch are assets.
What you’ll love about working here
Inspiring Mission
Join a high-potential biotech fighting antimicrobial resistance with cutting-edge science.
Strategic Impact
Lead global efforts to bring next-gen solutions to market and transform the fight against antibiotic resistance.
Growth Opportunities
Develop your skills and grow professionally in a dynamic environment.
Empowered Leadership
Drive change within a passionate team that supports and challenges each other to excel.
Attractive Compensation
Enjoy a competitive package aligned with your role and experience.
Work-Life Flexibility
Benefit from hybrid work and flexible hours tailored to your lifestyle.
Innovation Culture
Be part of a team that values collaboration, creativity, and mission-first thinking.
Fun & Team Spirit
Enjoy team breakfasts, lunches, afterworks, and memorable team-building moments.
Ready to make an impact?
We’d love to hear your story. Apply today!